Diagnosis: Male factor infertility complicated by DH's Robertsonian Translocation 13;15.
IVF #1 July 2006 (Pensacola, FL) 23 eggs retrieved. 18 fertilized via ICSI. PGD. 8 "normal" embryos. Freeze all cycle due to severe OHSS. Hospitalized for 8 days.
FET #1 November 2006 (Pensacola, FL) Canceled at the last minute (after taking all the meds and shots for about 3 weeks) due to nonsuppression.
FET #2 September 2007 (Pensacola, FL) Transferred 1 female embryo. BFN.
FET #3 November 2007 (Pensacola, FL) Transferred 2 male embryos. BFN.
Decided to change fertlility clinics, so consulted with CCRM in Denver and SIRM in Las Vegas. Chose CCRM and transferred remaining 5 frozen embryos from Pensacola to Denver to have them genetically re-checked. 3 embryos died upon thaw, 1 embryo's genetic test came back inconclusive. 1 embryo normal for chromosomes 13 & 15. Re-froze the one normal embryo and the one inconclusive embryo.
One-day work up at CCRM in April 2008. FSH 7.18, E2 29, AMH 4.3, AFC 35+, genetic testing on me all came back normal. DH's genetic testing came back with 65% of sperm are affected with the unbalanced translocation.
IVF #2 July 2008 (Denver, CO) 30 eggs retrieved. 26 mature. 23 fertilized via ICSI. PGD. 7 embryos normal for chromosomes 13 & 15. 1 embryo made it to freeze. Transferred 2 grade AA blasts. BFN.
IVF #3 November 2008 (Denver, CO) 34 eggs retrieved. 25 mature. 22 fertilized via ICSI. 15 blasts for CGH testing. Results: 8 abnormal & 7 no results. The 7 no results will be thawed, re-biopsied, and re-vitrified; and the cells will be sent for FISH analysis for the translocation. Should get those results by Christmas. UPDATE: 1 blast is normal for 13 & 15 and 1 blast still no result.
FET #4 February 2009 (Denver, CO) Our first ever BFP!! Beta #1 (9dp5dt): 174 !!!!! Beta #2 (11dp5dt): 401 !!!!!
As you may know, I've taken a hiatus from blogging, as I haven't been "together" enough to post my thoughts and feelings coherently. Everytime I start to blog, I would bawl my eyes out. I find that this past cycle is so hard to "get over". However, I don't think one ever "gets over" a failed cycle. Instead, one finds a way to move on. I guess technically, my last cycle wasn't a failed cycle - but I feel so down in the dumps about it nonetheless. You would think that after 3 IVFs and 3 FETs, I'd be used to this by now. After each cycle, it gets harder and harder for me to cope with the reality of our situation.
My husband and I have been keeping to ourselves lately. It's just so hard, especially pretending that everything is ok and putting on a fake smile for everyone. Christmas was extremely hard. We forced ourselves to go to Mass on Christmas Day, where it seems like everyone has a little one or two or more or they are either expecting. It took everything I had not to cry in the middle of church.
I'll post details of the FISH analysis later, probably tonight if I can stop crying long enough. Right now, I just want to let you all know that I'm having a really, really rough time and to please forgive me for not updating sooner. And I thank you, from the bottom of my infertile heart, for your comments, emails, and PMs. I will get to each and everyone of your blogs and catch up.