Diagnosis: Male factor infertility complicated by DH's Robertsonian Translocation 13;15.
IVF #1 July 2006 (Pensacola, FL) 23 eggs retrieved. 18 fertilized via ICSI. PGD. 8 "normal" embryos. Freeze all cycle due to severe OHSS. Hospitalized for 8 days.
FET #1 November 2006 (Pensacola, FL) Canceled at the last minute (after taking all the meds and shots for about 3 weeks) due to nonsuppression.
FET #2 September 2007 (Pensacola, FL) Transferred 1 female embryo. BFN.
FET #3 November 2007 (Pensacola, FL) Transferred 2 male embryos. BFN.
Decided to change fertlility clinics, so consulted with CCRM in Denver and SIRM in Las Vegas. Chose CCRM and transferred remaining 5 frozen embryos from Pensacola to Denver to have them genetically re-checked. 3 embryos died upon thaw, 1 embryo's genetic test came back inconclusive. 1 embryo normal for chromosomes 13 & 15. Re-froze the one normal embryo and the one inconclusive embryo.
One-day work up at CCRM in April 2008. FSH 7.18, E2 29, AMH 4.3, AFC 35+, genetic testing on me all came back normal. DH's genetic testing came back with 65% of sperm are affected with the unbalanced translocation.
IVF #2 July 2008 (Denver, CO) 30 eggs retrieved. 26 mature. 23 fertilized via ICSI. PGD. 7 embryos normal for chromosomes 13 & 15. 1 embryo made it to freeze. Transferred 2 grade AA blasts. BFN.
IVF #3 November 2008 (Denver, CO) 34 eggs retrieved. 25 mature. 22 fertilized via ICSI. 15 blasts for CGH testing. Results: 8 abnormal & 7 no results. The 7 no results will be thawed, re-biopsied, and re-vitrified; and the cells will be sent for FISH analysis for the translocation. Should get those results by Christmas. UPDATE: 1 blast is normal for 13 & 15 and 1 blast still no result.
FET #4 February 2009 (Denver, CO) Our first ever BFP!! Beta #1 (9dp5dt): 174 !!!!! Beta #2 (11dp5dt): 401 !!!!!
My nurse finally called me this evening. She said that Dr. Schoolcraft isn't concerned about the spotting or the E2 level. But if it would make me feel better, I could take one Estrace pill orally at bedtime. Then my next hormone check (E2 and P4) will be next Tuesday, same day as the ultrasound.
So the nurse called my pharmacy but they didn't have the name brand in stock but could get it by tomorrow. The prescription said name brand preferred, so Jerry had to call around to several different pharmacies and finally lucked out. So I start taking the Estrace pills tonight. I've taken the pills before - for FETs 1 through 3. I don't remember having any adverse reactions, but then I've never been pg while taking them. We'll see.
As for the spotting, I'm still having a little bit of brownish spotting (sorry, tmi I know). It freaks me out every single time. But other ladies on the boards I visit have had similar spotting (some much worse) and had a good outcome. So that's reassuring.
We're still taking it one step at a time, as that's all we can do right now. Thank you all for your prayers and positive vibes and support. It means more to me than you'll ever know. I will continue to keep ya'll in my prayers and hope for the best for each and everyone of you.